Impaired Self-Awareness of Motor Deficits in Parkinson's Disease: Association With Motor Asymmetry and Motor Phenotypes
Identifieur interne : 001091 ( Main/Exploration ); précédent : 001090; suivant : 001092Impaired Self-Awareness of Motor Deficits in Parkinson's Disease: Association With Motor Asymmetry and Motor Phenotypes
Auteurs : Franziska Maier [Allemagne] ; George P. Prigatano [États-Unis] ; Elke Kalbe [Allemagne] ; Michael T. Barbe [Allemagne] ; Carsten Eggers [Allemagne] ; Catharine J. Lewis [Allemagne] ; Richard S. Burns [États-Unis] ; Jeannine Morrone-Strupinsky [États-Unis] ; Guillermo Moguel-Cobos [États-Unis] ; Gereon R. Fink [Allemagne] ; Lars Timmermann [Allemagne]Source :
- Movement disorders [ 0885-3185 ] ; 2012.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Background: This study investigated impaired self-awareness of motor deficits in nondemented, nondepressed Parkinson's disease (PD) patients during a defined clinical on state. Methods: Twenty-eight PD patients were examined. Patients' self-ratings and experts' ratings of patients' motor performance were compared. Patient-examiner discrepancies and level of impairment determined severity of impaired self-awareness. Motor exam assessed overall motor functioning, hemibody impairment, and 4 motor phenotypes. Neuropsychological tests were also conducted. Results: Signs of impaired self-awareness were present in 17 patients (60.7%). Higher severity of impaired self-awareness correlated significantly with higher postural-instability and gait-difficulty off scores (r = .575; P = .001), overall motor off scores (r = .569; P = .002), and higher left hemibody off scores (r = .490; P = .008). In multiple linear regression analyses, higher postural-instability and gait-difficulty off scores remained as the only significant predictor of impaired self-awareness severity. Conclusions: Postural instability and gait difficulties, disease severity, and right hemisphere dysfunction seem to contribute to impaired self-awareness.
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 000071
- to stream PascalFrancis, to step Curation: 002C43
- to stream PascalFrancis, to step Checkpoint: 000164
- to stream Main, to step Merge: 001143
- to stream Main, to step Curation: 001091
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Impaired Self-Awareness of Motor Deficits in Parkinson's Disease: Association With Motor Asymmetry and Motor Phenotypes</title><author><name sortKey="Maier, Franziska" sort="Maier, Franziska" uniqKey="Maier F" first="Franziska" last="Maier">Franziska Maier</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Cologne</s1><s2>Cologne</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>University Hospital Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author><author><name sortKey="Prigatano, George P" sort="Prigatano, George P" uniqKey="Prigatano G" first="George P." last="Prigatano">George P. Prigatano</name><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Clinical Neuropsychology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center</s1><s2>Phoenix, Arizona</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Kalbe, Elke" sort="Kalbe, Elke" uniqKey="Kalbe E" first="Elke" last="Kalbe">Elke Kalbe</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Cologne</s1><s2>Cologne</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>University Hospital Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Institute of Neuroscience and Medicine, Cognitive Neurology Section, Research Center Jülich</s1><s3>DEU</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Research Center Jülich</wicri:noRegion><wicri:noRegion>Institute of Neuroscience and Medicine, Cognitive Neurology Section, Research Center Jülich</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Institute for Gerontology, University of Vechta</s1><s2>Vechta</s2><s3>DEU</s3><sZ>3 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Vechta</wicri:noRegion><wicri:noRegion>University of Vechta</wicri:noRegion><wicri:noRegion>Vechta</wicri:noRegion></affiliation></author><author><name sortKey="Barbe, Michael T" sort="Barbe, Michael T" uniqKey="Barbe M" first="Michael T." last="Barbe">Michael T. Barbe</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Cologne</s1><s2>Cologne</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>University Hospital Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Institute of Neuroscience and Medicine, Cognitive Neurology Section, Research Center Jülich</s1><s3>DEU</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Research Center Jülich</wicri:noRegion><wicri:noRegion>Institute of Neuroscience and Medicine, Cognitive Neurology Section, Research Center Jülich</wicri:noRegion></affiliation></author><author><name sortKey="Eggers, Carsten" sort="Eggers, Carsten" uniqKey="Eggers C" first="Carsten" last="Eggers">Carsten Eggers</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Cologne</s1><s2>Cologne</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>University Hospital Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author><author><name sortKey="Lewis, Catharine J" sort="Lewis, Catharine J" uniqKey="Lewis C" first="Catharine J." last="Lewis">Catharine J. Lewis</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Cologne</s1><s2>Cologne</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>University Hospital Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author><author><name sortKey="Burns, Richard S" sort="Burns, Richard S" uniqKey="Burns R" first="Richard S." last="Burns">Richard S. Burns</name><affiliation wicri:level="2"><inist:fA14 i1="05"><s1>Movement Disorders Clinic, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center</s1><s2>Phoenix, Arizona</s2><s3>USA</s3><sZ>7 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Morrone Strupinsky, Jeannine" sort="Morrone Strupinsky, Jeannine" uniqKey="Morrone Strupinsky J" first="Jeannine" last="Morrone-Strupinsky">Jeannine Morrone-Strupinsky</name><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Clinical Neuropsychology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center</s1><s2>Phoenix, Arizona</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Moguel Cobos, Guillermo" sort="Moguel Cobos, Guillermo" uniqKey="Moguel Cobos G" first="Guillermo" last="Moguel-Cobos">Guillermo Moguel-Cobos</name><affiliation wicri:level="2"><inist:fA14 i1="05"><s1>Movement Disorders Clinic, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center</s1><s2>Phoenix, Arizona</s2><s3>USA</s3><sZ>7 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Fink, Gereon R" sort="Fink, Gereon R" uniqKey="Fink G" first="Gereon R." last="Fink">Gereon R. Fink</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Cologne</s1><s2>Cologne</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>University Hospital Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Institute of Neuroscience and Medicine, Cognitive Neurology Section, Research Center Jülich</s1><s3>DEU</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Research Center Jülich</wicri:noRegion><wicri:noRegion>Institute of Neuroscience and Medicine, Cognitive Neurology Section, Research Center Jülich</wicri:noRegion></affiliation></author><author><name sortKey="Timmermann, Lars" sort="Timmermann, Lars" uniqKey="Timmermann L" first="Lars" last="Timmermann">Lars Timmermann</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Cologne</s1><s2>Cologne</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>University Hospital Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">12-0393093</idno><date when="2012">2012</date><idno type="stanalyst">PASCAL 12-0393093 INIST</idno><idno type="RBID">Pascal:12-0393093</idno><idno type="wicri:Area/PascalFrancis/Corpus">000071</idno><idno type="wicri:Area/PascalFrancis/Curation">002C43</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000164</idno><idno type="wicri:doubleKey">0885-3185:2012:Maier F:impaired:self:awareness</idno><idno type="wicri:Area/Main/Merge">001143</idno><idno type="wicri:Area/Main/Curation">001091</idno><idno type="wicri:Area/Main/Exploration">001091</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Impaired Self-Awareness of Motor Deficits in Parkinson's Disease: Association With Motor Asymmetry and Motor Phenotypes</title><author><name sortKey="Maier, Franziska" sort="Maier, Franziska" uniqKey="Maier F" first="Franziska" last="Maier">Franziska Maier</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Cologne</s1><s2>Cologne</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>University Hospital Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author><author><name sortKey="Prigatano, George P" sort="Prigatano, George P" uniqKey="Prigatano G" first="George P." last="Prigatano">George P. Prigatano</name><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Clinical Neuropsychology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center</s1><s2>Phoenix, Arizona</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Kalbe, Elke" sort="Kalbe, Elke" uniqKey="Kalbe E" first="Elke" last="Kalbe">Elke Kalbe</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Cologne</s1><s2>Cologne</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>University Hospital Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Institute of Neuroscience and Medicine, Cognitive Neurology Section, Research Center Jülich</s1><s3>DEU</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Research Center Jülich</wicri:noRegion><wicri:noRegion>Institute of Neuroscience and Medicine, Cognitive Neurology Section, Research Center Jülich</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Institute for Gerontology, University of Vechta</s1><s2>Vechta</s2><s3>DEU</s3><sZ>3 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Vechta</wicri:noRegion><wicri:noRegion>University of Vechta</wicri:noRegion><wicri:noRegion>Vechta</wicri:noRegion></affiliation></author><author><name sortKey="Barbe, Michael T" sort="Barbe, Michael T" uniqKey="Barbe M" first="Michael T." last="Barbe">Michael T. Barbe</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Cologne</s1><s2>Cologne</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>University Hospital Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Institute of Neuroscience and Medicine, Cognitive Neurology Section, Research Center Jülich</s1><s3>DEU</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Research Center Jülich</wicri:noRegion><wicri:noRegion>Institute of Neuroscience and Medicine, Cognitive Neurology Section, Research Center Jülich</wicri:noRegion></affiliation></author><author><name sortKey="Eggers, Carsten" sort="Eggers, Carsten" uniqKey="Eggers C" first="Carsten" last="Eggers">Carsten Eggers</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Cologne</s1><s2>Cologne</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>University Hospital Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author><author><name sortKey="Lewis, Catharine J" sort="Lewis, Catharine J" uniqKey="Lewis C" first="Catharine J." last="Lewis">Catharine J. Lewis</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Cologne</s1><s2>Cologne</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>University Hospital Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author><author><name sortKey="Burns, Richard S" sort="Burns, Richard S" uniqKey="Burns R" first="Richard S." last="Burns">Richard S. Burns</name><affiliation wicri:level="2"><inist:fA14 i1="05"><s1>Movement Disorders Clinic, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center</s1><s2>Phoenix, Arizona</s2><s3>USA</s3><sZ>7 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Morrone Strupinsky, Jeannine" sort="Morrone Strupinsky, Jeannine" uniqKey="Morrone Strupinsky J" first="Jeannine" last="Morrone-Strupinsky">Jeannine Morrone-Strupinsky</name><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Department of Clinical Neuropsychology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center</s1><s2>Phoenix, Arizona</s2><s3>USA</s3><sZ>2 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Moguel Cobos, Guillermo" sort="Moguel Cobos, Guillermo" uniqKey="Moguel Cobos G" first="Guillermo" last="Moguel-Cobos">Guillermo Moguel-Cobos</name><affiliation wicri:level="2"><inist:fA14 i1="05"><s1>Movement Disorders Clinic, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center</s1><s2>Phoenix, Arizona</s2><s3>USA</s3><sZ>7 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Fink, Gereon R" sort="Fink, Gereon R" uniqKey="Fink G" first="Gereon R." last="Fink">Gereon R. Fink</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Cologne</s1><s2>Cologne</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>University Hospital Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Institute of Neuroscience and Medicine, Cognitive Neurology Section, Research Center Jülich</s1><s3>DEU</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Research Center Jülich</wicri:noRegion><wicri:noRegion>Institute of Neuroscience and Medicine, Cognitive Neurology Section, Research Center Jülich</wicri:noRegion></affiliation></author><author><name sortKey="Timmermann, Lars" sort="Timmermann, Lars" uniqKey="Timmermann L" first="Lars" last="Timmermann">Lars Timmermann</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, University Hospital Cologne</s1><s2>Cologne</s2><s3>DEU</s3><sZ>1 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>University Hospital Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anosognosia</term><term>Asymmetry</term><term>Awareness</term><term>Motor system disorder</term><term>Nervous system diseases</term><term>Parkinson disease</term><term>Phenotype</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Trouble moteur</term><term>Maladie de Parkinson</term><term>Anosognosie</term><term>Pathologie du système nerveux</term><term>Prise conscience</term><term>Asymétrie</term><term>Phénotype</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background: This study investigated impaired self-awareness of motor deficits in nondemented, nondepressed Parkinson's disease (PD) patients during a defined clinical on state. Methods: Twenty-eight PD patients were examined. Patients' self-ratings and experts' ratings of patients' motor performance were compared. Patient-examiner discrepancies and level of impairment determined severity of impaired self-awareness. Motor exam assessed overall motor functioning, hemibody impairment, and 4 motor phenotypes. Neuropsychological tests were also conducted. Results: Signs of impaired self-awareness were present in 17 patients (60.7%). Higher severity of impaired self-awareness correlated significantly with higher postural-instability and gait-difficulty off scores (r = .575; P = .001), overall motor off scores (r = .569; P = .002), and higher left hemibody off scores (r = .490; P = .008). In multiple linear regression analyses, higher postural-instability and gait-difficulty off scores remained as the only significant predictor of impaired self-awareness severity. Conclusions: Postural instability and gait difficulties, disease severity, and right hemisphere dysfunction seem to contribute to impaired self-awareness.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>États-Unis</li></country><region><li>Arizona</li></region></list><tree><country name="Allemagne"><noRegion><name sortKey="Maier, Franziska" sort="Maier, Franziska" uniqKey="Maier F" first="Franziska" last="Maier">Franziska Maier</name></noRegion><name sortKey="Barbe, Michael T" sort="Barbe, Michael T" uniqKey="Barbe M" first="Michael T." last="Barbe">Michael T. Barbe</name><name sortKey="Barbe, Michael T" sort="Barbe, Michael T" uniqKey="Barbe M" first="Michael T." last="Barbe">Michael T. Barbe</name><name sortKey="Eggers, Carsten" sort="Eggers, Carsten" uniqKey="Eggers C" first="Carsten" last="Eggers">Carsten Eggers</name><name sortKey="Fink, Gereon R" sort="Fink, Gereon R" uniqKey="Fink G" first="Gereon R." last="Fink">Gereon R. Fink</name><name sortKey="Fink, Gereon R" sort="Fink, Gereon R" uniqKey="Fink G" first="Gereon R." last="Fink">Gereon R. Fink</name><name sortKey="Kalbe, Elke" sort="Kalbe, Elke" uniqKey="Kalbe E" first="Elke" last="Kalbe">Elke Kalbe</name><name sortKey="Kalbe, Elke" sort="Kalbe, Elke" uniqKey="Kalbe E" first="Elke" last="Kalbe">Elke Kalbe</name><name sortKey="Kalbe, Elke" sort="Kalbe, Elke" uniqKey="Kalbe E" first="Elke" last="Kalbe">Elke Kalbe</name><name sortKey="Lewis, Catharine J" sort="Lewis, Catharine J" uniqKey="Lewis C" first="Catharine J." last="Lewis">Catharine J. Lewis</name><name sortKey="Timmermann, Lars" sort="Timmermann, Lars" uniqKey="Timmermann L" first="Lars" last="Timmermann">Lars Timmermann</name></country><country name="États-Unis"><region name="Arizona"><name sortKey="Prigatano, George P" sort="Prigatano, George P" uniqKey="Prigatano G" first="George P." last="Prigatano">George P. Prigatano</name></region><name sortKey="Burns, Richard S" sort="Burns, Richard S" uniqKey="Burns R" first="Richard S." last="Burns">Richard S. Burns</name><name sortKey="Moguel Cobos, Guillermo" sort="Moguel Cobos, Guillermo" uniqKey="Moguel Cobos G" first="Guillermo" last="Moguel-Cobos">Guillermo Moguel-Cobos</name><name sortKey="Morrone Strupinsky, Jeannine" sort="Morrone Strupinsky, Jeannine" uniqKey="Morrone Strupinsky J" first="Jeannine" last="Morrone-Strupinsky">Jeannine Morrone-Strupinsky</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001091 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001091 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Main
|étape= Exploration
|type= RBID
|clé= Pascal:12-0393093
|texte= Impaired Self-Awareness of Motor Deficits in Parkinson's Disease: Association With Motor Asymmetry and Motor Phenotypes
}}
| This area was generated with Dilib version V0.6.23. |  |